Cargando…

Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts

INTRODUCTION: Toll-like receptors (TLRs) are likely to play crucial roles in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to determine the key TLRs in synovium and explore their roles in the activation of fibroblast-like synoviocytes (FLSs) mediated by T cells in arthriti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Wenhua, Meng, Liesu, Jiang, Congshan, He, Xiaojing, Hou, Weikun, Xu, Peng, Du, Heng, Holmdahl, Rikard, Lu, Shemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218918/ https://www.ncbi.nlm.nih.gov/pubmed/21708001 http://dx.doi.org/10.1186/ar3384

Ejemplares similares

Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
por: Meng, Liesu, et al.
Publicado: (2010)

MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats
por: Jiang, Congshan, et al.
Publicado: (2014)

MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis
por: Wang, Si, et al.
Publicado: (2021)

IL-22 expression is increased variedly in the initial phase, onset and chronic phase of a pristane-induced arthritis rat model
por: Hou, Weikun, et al.
Publicado: (2017)

Increased expression of Th17 cytokines and interleukin-22 correlates with disease activity in pristane-induced arthritis in rats
por: Wang, Bo, et al.
Publicado: (2017)

Successful Transfection of MicroRNA Mimics or Inhibitors in a Regular Cell Line and in Primary Cells Derived from Patients with Rheumatoid Arthritis
por: Wang, Si, et al.
Publicado: (2023)

Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages
por: Zhu, Wenhua, et al.
Publicado: (2020)

Activation of synovial fibroblasts via Toll-like receptor signaling
por: Kyburz, D, et al.
Publicado: (2003)

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice
por: Li, Mengyao, et al.
Publicado: (2021)

Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements
por: Jiang, Congshan, et al.
Publicado: (2019)

Interpreting the MicroRNA-15/107 family: interaction identification by combining network based and experiment supported approach
por: Wang, Si, et al.
Publicado: (2019)

Evaluation of immunoprotection against coronavirus disease 2019: Novel variants, vaccine inoculation, and complications
por: Jiang, Congshan, et al.
Publicado: (2023)

Toll-like receptor expression in synovial fibroblasts and normal skin fibroblasts and induction of matrix metallo-proteinase expression by various Toll-like receptor ligands
por: Kyburz, D, et al.
Publicado: (2005)

Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis
por: Hu, Fanlei, et al.
Publicado: (2014)

Upregulating miR-27a-3p inhibits cell proliferation and inflammation of rheumatoid arthritis synovial fibroblasts through targeting toll-like receptor 5
por: Chen, Lifeng, et al.
Publicado: (2021)

SLC38A6 expression in macrophages exacerbates pulmonary inflammation
por: Peng, Yizhao, et al.
Publicado: (2023)

Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes
por: Xu, Jing, et al.
Publicado: (2020)

The involvement of Toll‐like receptor 9 in the pathogenesis of erosive autoimmune arthritis
por: Fischer, Anita, et al.
Publicado: (2018)

Soluble CD14 Induces Pro-inflammatory Cytokines in Rheumatoid Arthritis Fibroblast-Like Synovial Cells via Toll-Like Receptor 4
por: Ichise, Yoshihide, et al.
Publicado: (2020)

Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification
por: Li, Xiaowei, et al.
Publicado: (2021)

TLR3 and TLR7 Modulate IgE Production in Antigen Induced Pulmonary Inflammation via Influencing IL-4 Expression in Immune Organs
por: Meng, Liesu, et al.
Publicado: (2011)

Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax
por: Wang, Bo, et al.
Publicado: (2020)

Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts
por: Kullmann , Frank, et al.
Publicado: (1999)

IL-29 enhances Toll-like receptor-mediated IL-6 and IL-8 production by the synovial fibroblasts from rheumatoid arthritis patients
por: Xu, Lingxiao, et al.
Publicado: (2013)

Constitutive upregulation of the transforming growth factor-β pathway in rheumatoid arthritis synovial fibroblasts
por: Pohlers, Dirk, et al.
Publicado: (2007)

The Expression of Inflammasomes NLRP1 and NLRP3, Toll-Like Receptors, and Vitamin D Receptor in Synovial Fibroblasts From Patients With Different Types of Knee Arthritis
por: Sakalyte, Regina, et al.
Publicado: (2022)

Molecular detection of SARS-CoV-2 being challenged by virus variation and asymptomatic infection
por: Jiang, Congshan, et al.
Publicado: (2021)

HMGB1–LPS complex promotes transformation of osteoarthritis synovial fibroblasts to a rheumatoid arthritis synovial fibroblast-like phenotype
por: Qin, Y, et al.
Publicado: (2014)

The anti-microbial peptide rCRAMP is strongly upregulated during experimental arthritis in the rat
por: Hoffmann, Markus H, et al.
Publicado: (2011)

Activation of Synovial Fibroblasts in Rheumatoid Arthritis
por: Gay, Steffen, et al.
Publicado: (2000)

Fibroblast biology: Development and differentiation of synovial fibroblasts in arthritis
por: Edwards, Jonathan CW
Publicado: (2000)

Fibroblast biology: Signals targeting the synovial fibroblast in arthritis
por: Konttinen, Yrjö T, et al.
Publicado: (2000)

Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts
por: Agarwal, Sandeep K, et al.
Publicado: (2011)

The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models
por: Hagert, Cecilia, et al.
Publicado: (2018)

Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing
por: Jiang, Congshan, et al.
Publicado: (2016)

Real-world effectiveness and protection of SARS-CoV-2 vaccine among patients hospitalized for COVID-19 in Xi’an, China, December 8, 2021, to January 20, 2022: A retrospective study
por: Li, Xiaowei, et al.
Publicado: (2022)

Fibroblast biology: Effector signals released by the synovial fibroblast in arthritis
por: Ritchlin, Christopher
Publicado: (2000)

Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
por: Pap, Thomas, et al.
Publicado: (2000)

Genetic Studies in Experimental Arthritis
por: Holmdahl, Rikard
Publicado: (2000)

Association of MHC and rheumatoid arthritis: Why is rheumatoid arthritis associated with the MHC genetic region? An introduction
por: Holmdahl, Rikard
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_6vkopit2g511r2i7gr0ea0vlof