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Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays?
In vivo transplantation is the current 'gold-standard' assay for evaluating mammary stem cell (MaSC) function. Matrigel, a reconstituted extracellular matrix derived from a mouse sarcoma line, is increasingly being utilized for mammary repopulating assays, although original studies were ca...
Autores principales: | Vaillant, François, Lindeman, Geoffrey J, Visvader, Jane E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218928/ https://www.ncbi.nlm.nih.gov/pubmed/21635708 http://dx.doi.org/10.1186/bcr2851 |
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