Cargando…

miR-200c at the nexus of epithelial-mesenchymal transition, resistance to apoptosis, and the breast cancer stem cell phenotype

Decreased expression of miRNAs of the miR-200 family has been implicated in the growth and metastasis of breast cancer cells. Of this family, miR-200c has garnered particular attention as a consequence of its ability to target ZEB1 and ZEB2, mediators of epithelial- mesenchymal transition. An articl...

Descripción completa

Detalles Bibliográficos
Autor principal:	Radisky, Derek C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Editorial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218941/ https://www.ncbi.nlm.nih.gov/pubmed/21682933 http://dx.doi.org/10.1186/bcr2885

Ejemplares similares

MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell
por: Lu, Yuhua, et al.
Publicado: (2014)

Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition
por: Haraguchi, Takeshi, et al.
Publicado: (2016)

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles
por: Bhome, Rahul, et al.
Publicado: (2022)

Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer
por: Radisky, Evette S., et al.
Publicado: (2010)

Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels
por: Lee, Yang-ja, et al.
Publicado: (2018)

miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition
por: Sulaiman, Siti A., et al.
Publicado: (2016)

miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas
por: Tseng, Jill H., et al.
Publicado: (2017)

Epithelial down‐regulation of the miR‐200 family in fibrostenosing Crohn's disease is associated with features of epithelial to mesenchymal transition
por: Mehta, Shameer J., et al.
Publicado: (2018)

The Kindlin-2 regulation of epithelial-to-mesenchymal transition in breast cancer metastasis is mediated through miR-200b
por: Sossey-Alaoui, Khalid, et al.
Publicado: (2018)

Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells
por: Wang, Qian, et al.
Publicado: (2017)

The miR-200 Family of microRNAs: Fine Tuners of Epithelial-Mesenchymal Transition and Circulating Cancer Biomarkers
por: Cavallari, Ilaria, et al.
Publicado: (2021)

Effect of Huai Qi Huang on Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells through miR-200a
por: Pu, Jinyun, et al.
Publicado: (2016)

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer
por: Meng, Xiaodan, et al.
Publicado: (2016)

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
por: Gregory, Philip A., et al.
Publicado: (2011)

Curcumin Modifies Epithelial–Mesenchymal Transition in Colorectal Cancer Through Regulation of miR-200c/EPM5
por: Wang, Hui, et al.
Publicado: (2020)

miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells
por: Chen, Y, et al.
Publicado: (2013)

The Tetraindole SK228 Reverses the Epithelial-to-Mesenchymal Transition of Breast Cancer Cells by Up-Regulating Members of the miR-200 Family
por: Wang, Chie-Hong, et al.
Publicado: (2014)

MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
por: Xue, Xiaofeng, et al.
Publicado: (2014)

MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients
por: Pichler, M, et al.
Publicado: (2014)

AXL induces epithelial to mesenchymal transition and regulates the function of breast cancer stem cells
por: Asiedu, Michael K., et al.
Publicado: (2013)

Regulation of Epithelial-Mesenchymal Transition in Breast Cancer Cells by Cell Contact and Adhesion
por: Cichon, Magdalena A, et al.
Publicado: (2015)

A central role for MeCP2 in the epigenetic repression of miR-200c during epithelial-to-mesenchymal transition of glioma
por: Bian, Erbao, et al.
Publicado: (2019)

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-κB-dependent activation of Snail
por: Cichon, Magdalena A., et al.
Publicado: (2014)

miR-506 Regulates Epithelial Mesenchymal Transition in Breast Cancer Cell Lines
por: Arora, Himanshu, et al.
Publicado: (2013)

ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas
por: Sommerova, Lucia, et al.
Publicado: (2020)

The miR-200 Family: Versatile Players in Epithelial Ovarian Cancer
por: Muralidhar, Goda G., et al.
Publicado: (2015)

Regulation of cell growth and migration by miR-96 and miR-183 in a breast cancer model of epithelial-mesenchymal transition
por: Anderson, Olivia, et al.
Publicado: (2020)

MiR200 and miR302: Two Big Families Influencing Stem Cell Behavior †
por: Balzano, Francesca, et al.
Publicado: (2018)

Down‐regulation of microRNAs of the miR‐200 family and up‐regulation of Snail and Slug in inflammatory bowel diseases — hallmark of epithelial−mesenchymal transition
por: Zidar, Nina, et al.
Publicado: (2016)

Arrestin Domain Containing 3 Reverses Epithelial to Mesenchymal Transition and Chemo-Resistance of TNBC Cells by Up-Regulating Expression of miR-200b
por: Soung, Young Hwa, et al.
Publicado: (2019)

circ-ZEB1 regulates epithelial-mesenchymal transition and chemotherapy resistance of colorectal cancer through acting on miR-200c-5p
por: Chen, Hongyu, et al.
Publicado: (2022)

MiR-124 targets Slug to regulate epithelial–mesenchymal transition and metastasis of breast cancer
por: Liang, Yong-Jun, et al.
Publicado: (2013)

Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model
por: Banyard, Jacqueline, et al.
Publicado: (2013)

MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes
por: Yan, Li, et al.
Publicado: (2016)

Tumor-promoting properties of miR-8084 in breast cancer through enhancing proliferation, suppressing apoptosis and inducing epithelial–mesenchymal transition
por: Gao, Yujing, et al.
Publicado: (2018)

Long noncoding RNA ATB promotes the epithelial−mesenchymal transition by upregulating the miR-200c/Twist1 axe and predicts poor prognosis in breast cancer
por: Li, Rong-Hui, et al.
Publicado: (2018)

Extracellular matrix as a contextual determinant of transforming growth factor-β signaling in epithelial-mesenchymal transition and in cancer
por: Cichon, Magdalena A, et al.
Publicado: (2014)

Restoration of miR-1228* Expression Suppresses Epithelial-Mesenchymal Transition in Gastric Cancer
por: Jia, Litao, et al.
Publicado: (2013)

miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis, Migration and Invasion
por: Chen, Dahu, et al.
Publicado: (2014)

miR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition
por: Wang, Lin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_lvpgob63vppa8o689g5maidud2