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NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications
INTRODUCTION: Women with triple-negative breast cancer have the worst prognosis, frequently present with metastatic tumors and have few targeted therapy options. Notch-1 and Notch-4 are potent breast oncogenes that are overexpressed in triple-negative and other subtypes of breast cancer. PEA3, an ET...
Autores principales: | Clementz, Anthony G, Rogowski, Allison, Pandya, Kinnari, Miele, Lucio, Osipo, Clodia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218952/ https://www.ncbi.nlm.nih.gov/pubmed/21679465 http://dx.doi.org/10.1186/bcr2900 |
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