Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3

INTRODUCTION: Metastasis is a common event and the main cause of death in cancer patients. Lymphangiogenesis refers to the formation of new lymphatic vessels and is thought to be involved in the development of metastasis. Sunitinib is a multi-kinase inhibitor that blocks receptor tyrosine kinase act...

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Detalles Bibliográficos
Autores principales: Kodera, Yasuo, Katanasaka, Yasufumi, Kitamura, Yuka, Tsuda, Hitoshi, Nishio, Kazuto, Tamura, Tomohide, Koizumi, Fumiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218955/
https://www.ncbi.nlm.nih.gov/pubmed/21693010
http://dx.doi.org/10.1186/bcr2903

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