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Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

INTRODUCTION: Despite the benefits of estrogen receptor (ER)-targeted endocrine therapies in breast cancer, many tumors develop resistance. 14-3-3 ζ/YWHAZ, a member of the 14-3-3 family of conserved proteins, is over-expressed in several types of cancer, and our previous work showed that high expres...

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Detalles Bibliográficos
Autores principales: Bergamaschi, Anna, Christensen, Barbara L, Katzenellenbogen, Benita S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218959/
https://www.ncbi.nlm.nih.gov/pubmed/21707964
http://dx.doi.org/10.1186/bcr2913