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Prone position and recruitment manoeuvre: the combined effect improves oxygenation
INTRODUCTION: Among the various methods for improving oxygenation while decreasing the risk of ventilation-induced lung injury in patients with acute respiratory distress syndrome (ARDS), a ventilation strategy combining prone position (PP) and recruitment manoeuvres (RMs) can be practiced. We studi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218988/ https://www.ncbi.nlm.nih.gov/pubmed/21575205 http://dx.doi.org/10.1186/cc10235 |
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author | Rival, Gilles Patry, Cyrille Floret, Nathalie Navellou, Jean Christophe Belle, Evelyne Capellier, Gilles |
author_facet | Rival, Gilles Patry, Cyrille Floret, Nathalie Navellou, Jean Christophe Belle, Evelyne Capellier, Gilles |
author_sort | Rival, Gilles |
collection | PubMed |
description | INTRODUCTION: Among the various methods for improving oxygenation while decreasing the risk of ventilation-induced lung injury in patients with acute respiratory distress syndrome (ARDS), a ventilation strategy combining prone position (PP) and recruitment manoeuvres (RMs) can be practiced. We studied the effects on oxygenation of both RM and PP applied in early ARDS patients. METHODS: We conducted a prospective study. Sixteen consecutive patients with early ARDS fulfilling our criteria (ratio of arterial oxygen partial pressure to fraction of inspired oxygen (PaO(2)/FiO(2)) 98.3 ± 28 mmHg; positive end expiratory pressure, 10.7 ± 2.8 cmH(2)O) were analysed. Each patient was ventilated in both the supine position (SP) and the PP (six hours in each position). A 45 cmH(2)O extended sigh in pressure control mode was performed at the beginning of SP (RM1), one hour after turning to the PP (RM2) and at the end of the six-hour PP period (RM3). RESULTS: The mean arterial oxygen partial pressure (PaO(2)) changes after RM1, RM2 and RM3 were 9.6%, 15% and 19%, respectively. The PaO(2 )improvement after a single RM was significant after RM3 only (P < 0.05). Improvements in PaO(2 )level and PaO(2)/FiO(2 )ratio were transient in SP but durable during PP. PaO(2)/FiO(2 )ratio peaked at 218 mmHg after RM3. PaO(2)/FiO(2 )changes were significant only after RM3 and in the pulmonary ARDS group (P = 0.008). This global strategy had a benefit with regard to oxygenation: PaO(2)/FiO(2 )ratio increased from 98.3 mmHg to 165.6 mmHg 13 hours later at the end of the study (P < 0.05). Plateau airway pressures decreased after each RM and over the entire PP period and significantly after RM3 (P = 0.02). Some reversible side effects such as significant blood arterial pressure variations were found when extended sighs were performed. CONCLUSIONS: In our study, interventions such as a 45 cmH(2)O extended sigh during PP resulted in marked oxygenation improvement. Combined RM and PP led to the highest increase in PaO(2)/FiO(2 )ratio without major clinical side effects. |
format | Online Article Text |
id | pubmed-3218988 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-32189882011-11-17 Prone position and recruitment manoeuvre: the combined effect improves oxygenation Rival, Gilles Patry, Cyrille Floret, Nathalie Navellou, Jean Christophe Belle, Evelyne Capellier, Gilles Crit Care Research INTRODUCTION: Among the various methods for improving oxygenation while decreasing the risk of ventilation-induced lung injury in patients with acute respiratory distress syndrome (ARDS), a ventilation strategy combining prone position (PP) and recruitment manoeuvres (RMs) can be practiced. We studied the effects on oxygenation of both RM and PP applied in early ARDS patients. METHODS: We conducted a prospective study. Sixteen consecutive patients with early ARDS fulfilling our criteria (ratio of arterial oxygen partial pressure to fraction of inspired oxygen (PaO(2)/FiO(2)) 98.3 ± 28 mmHg; positive end expiratory pressure, 10.7 ± 2.8 cmH(2)O) were analysed. Each patient was ventilated in both the supine position (SP) and the PP (six hours in each position). A 45 cmH(2)O extended sigh in pressure control mode was performed at the beginning of SP (RM1), one hour after turning to the PP (RM2) and at the end of the six-hour PP period (RM3). RESULTS: The mean arterial oxygen partial pressure (PaO(2)) changes after RM1, RM2 and RM3 were 9.6%, 15% and 19%, respectively. The PaO(2 )improvement after a single RM was significant after RM3 only (P < 0.05). Improvements in PaO(2 )level and PaO(2)/FiO(2 )ratio were transient in SP but durable during PP. PaO(2)/FiO(2 )ratio peaked at 218 mmHg after RM3. PaO(2)/FiO(2 )changes were significant only after RM3 and in the pulmonary ARDS group (P = 0.008). This global strategy had a benefit with regard to oxygenation: PaO(2)/FiO(2 )ratio increased from 98.3 mmHg to 165.6 mmHg 13 hours later at the end of the study (P < 0.05). Plateau airway pressures decreased after each RM and over the entire PP period and significantly after RM3 (P = 0.02). Some reversible side effects such as significant blood arterial pressure variations were found when extended sighs were performed. CONCLUSIONS: In our study, interventions such as a 45 cmH(2)O extended sigh during PP resulted in marked oxygenation improvement. Combined RM and PP led to the highest increase in PaO(2)/FiO(2 )ratio without major clinical side effects. BioMed Central 2011 2011-05-16 /pmc/articles/PMC3218988/ /pubmed/21575205 http://dx.doi.org/10.1186/cc10235 Text en Copyright ©2011 Rival et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Rival, Gilles Patry, Cyrille Floret, Nathalie Navellou, Jean Christophe Belle, Evelyne Capellier, Gilles Prone position and recruitment manoeuvre: the combined effect improves oxygenation |
title | Prone position and recruitment manoeuvre: the combined effect improves oxygenation |
title_full | Prone position and recruitment manoeuvre: the combined effect improves oxygenation |
title_fullStr | Prone position and recruitment manoeuvre: the combined effect improves oxygenation |
title_full_unstemmed | Prone position and recruitment manoeuvre: the combined effect improves oxygenation |
title_short | Prone position and recruitment manoeuvre: the combined effect improves oxygenation |
title_sort | prone position and recruitment manoeuvre: the combined effect improves oxygenation |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218988/ https://www.ncbi.nlm.nih.gov/pubmed/21575205 http://dx.doi.org/10.1186/cc10235 |
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