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Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin

INTRODUCTION: Soluble amyloid precursor protein α (sAPPα) is a proteolyte of APP cleavage by α-secretase. The significance of the cleavage and the physiological role of sAPPα are unknown. A crystal structure of a region of the amino terminal of sAPPα reveals a domain that is similar to cysteine-rich...

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Detalles Bibliográficos
Autores principales: Demars, Michael P, Bartholomew, Amelia, Strakova, Zuzana, Lazarov, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219067/
https://www.ncbi.nlm.nih.gov/pubmed/21878106
http://dx.doi.org/10.1186/scrt77