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Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin
INTRODUCTION: Soluble amyloid precursor protein α (sAPPα) is a proteolyte of APP cleavage by α-secretase. The significance of the cleavage and the physiological role of sAPPα are unknown. A crystal structure of a region of the amino terminal of sAPPα reveals a domain that is similar to cysteine-rich...
Autores principales: | Demars, Michael P, Bartholomew, Amelia, Strakova, Zuzana, Lazarov, Orly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219067/ https://www.ncbi.nlm.nih.gov/pubmed/21878106 http://dx.doi.org/10.1186/scrt77 |
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