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βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis
During eye development, apoptosis is vital to the maturation of highly specialized structures such as the lens and retina. Several forms of apoptosis have been described, including anoikis, a form of apoptosis triggered by inadequate or inappropriate cell–matrix contacts. The anoikis regulators, Bit...
Autores principales: | Ma, B, Sen, T, Asnaghi, L, Valapala, M, Yang, F, Hose, S, McLeod, D S, Lu, Y, Eberhart, C, Zigler, J S, Sinha, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219085/ https://www.ncbi.nlm.nih.gov/pubmed/21993393 http://dx.doi.org/10.1038/cddis.2011.100 |
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