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Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation

INTRODUCTION: Expression of Y-box binding protein-1 (YB-1) is associated with tumor progression and drug resistance. Phosphorylation of YB-1 at serine residue 102 (S102) in response to growth factors is required for its transcriptional activity and is thought to be regulated by cytoplasmic signaling...

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Detalles Bibliográficos
Autores principales: Toulany, Mahmoud, Schickfluß, Tim-Andre, Eicheler, Wolfgang, Kehlbach, Rainer, Schittek, Birgit, Rodemann, H Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219189/
https://www.ncbi.nlm.nih.gov/pubmed/21392397
http://dx.doi.org/10.1186/bcr2845