The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines

INTRODUCTION: Indole-3-carbinol (I3C), an autolysis product of glucosinolates present in cruciferous vegetables, and its dimeric derivative (3,3'-DIM) have been indicated as promising agents in preventing the development and progression of breast cancer. We have recently shown that I3C cyclic t...

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Detalles Bibliográficos
Autores principales: De Santi, Mauro, Galluzzi, Luca, Lucarini, Simone, Paoletti, Maria Filomena, Fraternale, Alessandra, Duranti, Andrea, De Marco, Cinzia, Fanelli, Mirco, Zaffaroni, Nadia, Brandi, Giorgio, Magnani, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219196/
https://www.ncbi.nlm.nih.gov/pubmed/21435243
http://dx.doi.org/10.1186/bcr2855

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