Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer

INTRODUCTION: Estrogen receptor-negative (ER-) breast cancer is a heterogeneous disease with limited therapeutic options. The molecular apocrine subtype constitutes 50% of ER-tumors and is characterized by overexpression of steroid response genes including androgen receptor (AR). We have recently id...

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Detalles Bibliográficos
Autores principales: Naderi, Ali, Chia, Kee Ming, Liu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219199/
https://www.ncbi.nlm.nih.gov/pubmed/21457548
http://dx.doi.org/10.1186/bcr2858

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