miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: a potential for therapeutic intervention

INTRODUCTION: New levels of gene regulation with microRNA (miR) and gene copy number alterations (CNAs) have been identified as playing a role in various cancers. We have previously reported that sporadic breast cancer tissues exhibit significant alteration in H2AX gene copy number. However, how CNA...

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Detalles Bibliográficos
Autores principales: Srivastava, Niloo, Manvati, Siddharth, Srivastava, Archita, Pal, Ranjana, Kalaiarasan, Ponnusamy, Chattopadhyay, Shilpi, Gochhait, Sailesh, Dua, Raina, Bamezai, Rameshwar NK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219202/
https://www.ncbi.nlm.nih.gov/pubmed/21463514
http://dx.doi.org/10.1186/bcr2861

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