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Targets of miR-200c mediate suppression of cell motility and anoikis resistance
INTRODUCTION: miR-200c and other members of the miR-200 family promote epithelial identity by directly targeting ZEB1 and ZEB2, which repress E-cadherin and other genes involved in polarity. Loss of miR-200c is often observed in carcinoma cells that have undergone epithelial to mesenchymal transitio...
Autores principales: | Howe, Erin N, Cochrane, Dawn R, Richer, Jennifer K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219208/ https://www.ncbi.nlm.nih.gov/pubmed/21501518 http://dx.doi.org/10.1186/bcr2867 |
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