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The therapeutic potential of a venomous lizard: the use of glucagon-like peptide-1 analogues in the critically ill
Glucagon-like peptide-1 (GLP-1), a principal mediator of the postprandial insulinotropic response in health, has a half-life of minutes. The saliva of the Gila monster contains exendin-4, a structural analogue of human GLP-1, but with a much longer half-life. A synthetic preparation of exendin-4, ex...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219279/ https://www.ncbi.nlm.nih.gov/pubmed/20979668 http://dx.doi.org/10.1186/cc9281 |