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Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!

The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association wi...

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Detalles Bibliográficos
Autores principales: Reed, Matthew J, Lone, Nazir, Walsh, Timothy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219305/
https://www.ncbi.nlm.nih.gov/pubmed/21371347
http://dx.doi.org/10.1186/cc10014
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author Reed, Matthew J
Lone, Nazir
Walsh, Timothy S
author_facet Reed, Matthew J
Lone, Nazir
Walsh, Timothy S
author_sort Reed, Matthew J
collection PubMed
description The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association with modern trauma care is poorly described. In addition, early predictors of massive transfusion, which might trigger a proactive haemostatic resuscitation strategy, are not currently available. We review recent literature relating to predictors of massive transfusions and the relationship between transfusion and mortality.
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spelling pubmed-32193052012-03-01 Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please! Reed, Matthew J Lone, Nazir Walsh, Timothy S Crit Care Commentary The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association with modern trauma care is poorly described. In addition, early predictors of massive transfusion, which might trigger a proactive haemostatic resuscitation strategy, are not currently available. We review recent literature relating to predictors of massive transfusions and the relationship between transfusion and mortality. BioMed Central 2011 2011-03-01 /pmc/articles/PMC3219305/ /pubmed/21371347 http://dx.doi.org/10.1186/cc10014 Text en Copyright ©2011 BioMed Central Ltd
spellingShingle Commentary
Reed, Matthew J
Lone, Nazir
Walsh, Timothy S
Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
title Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
title_full Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
title_fullStr Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
title_full_unstemmed Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
title_short Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
title_sort resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219305/
https://www.ncbi.nlm.nih.gov/pubmed/21371347
http://dx.doi.org/10.1186/cc10014
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