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Inhibition of cerebrovascular raf activation attenuates cerebral blood flow and prevents upregulation of contractile receptors after subarachnoid hemorrhage

BACKGROUND: Late cerebral ischemia carries high morbidity and mortality after subarachnoid hemorrhage (SAH) due to reduced cerebral blood flow (CBF) and the subsequent cerebral ischemia which is associated with upregulation of contractile receptors in the vascular smooth muscle cells (SMC) via activ...

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Detalles Bibliográficos
Autores principales: Ansar, Saema, Maddahi, Aida, Edvinsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219635/
https://www.ncbi.nlm.nih.gov/pubmed/22032648
http://dx.doi.org/10.1186/1471-2202-12-107