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Sleep-Dependent Facilitation of Episodic Memory Details
While a role for sleep in declarative memory processing is established, the qualitative nature of this consolidation benefit, and the physiological mechanisms mediating it, remain debated. Here, we investigate the impact of sleep physiology on characteristics of episodic memory using an item- (memor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219667/ https://www.ncbi.nlm.nih.gov/pubmed/22114672 http://dx.doi.org/10.1371/journal.pone.0027421 |
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author | van der Helm, Els Gujar, Ninad Nishida, Masaki Walker, Matthew P. |
author_facet | van der Helm, Els Gujar, Ninad Nishida, Masaki Walker, Matthew P. |
author_sort | van der Helm, Els |
collection | PubMed |
description | While a role for sleep in declarative memory processing is established, the qualitative nature of this consolidation benefit, and the physiological mechanisms mediating it, remain debated. Here, we investigate the impact of sleep physiology on characteristics of episodic memory using an item- (memory elements) and context- (contextual details associated with those elements) learning paradigm; the latter being especially dependent on the hippocampus. Following back-to-back encoding of two word lists, each associated with a different context, participants were assigned to either a Nap-group, who obtained a 120-min nap, or a No Nap-group. Six hours post-encoding, participants performed a recognition test involving item-memory and context-memory judgments. In contrast to item-memory, which demonstrated no between-group differences, a significant benefit in context-memory developed in the Nap-group, the extent of which correlated both with the amount of stage-2 NREM sleep and frontal fast sleep-spindles. Furthermore, a difference was observed on the basis of word-list order, with the sleep benefit and associated physiological correlations being selective for the second word-list, learned last (most proximal to sleep). These findings suggest that sleep may preferentially benefit contextual (hippocampal-dependent) aspects of memory, supported by sleep-spindle oscillations, and that the temporal order of initial learning differentially determines subsequent offline consolidation. |
format | Online Article Text |
id | pubmed-3219667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-32196672011-11-23 Sleep-Dependent Facilitation of Episodic Memory Details van der Helm, Els Gujar, Ninad Nishida, Masaki Walker, Matthew P. PLoS One Research Article While a role for sleep in declarative memory processing is established, the qualitative nature of this consolidation benefit, and the physiological mechanisms mediating it, remain debated. Here, we investigate the impact of sleep physiology on characteristics of episodic memory using an item- (memory elements) and context- (contextual details associated with those elements) learning paradigm; the latter being especially dependent on the hippocampus. Following back-to-back encoding of two word lists, each associated with a different context, participants were assigned to either a Nap-group, who obtained a 120-min nap, or a No Nap-group. Six hours post-encoding, participants performed a recognition test involving item-memory and context-memory judgments. In contrast to item-memory, which demonstrated no between-group differences, a significant benefit in context-memory developed in the Nap-group, the extent of which correlated both with the amount of stage-2 NREM sleep and frontal fast sleep-spindles. Furthermore, a difference was observed on the basis of word-list order, with the sleep benefit and associated physiological correlations being selective for the second word-list, learned last (most proximal to sleep). These findings suggest that sleep may preferentially benefit contextual (hippocampal-dependent) aspects of memory, supported by sleep-spindle oscillations, and that the temporal order of initial learning differentially determines subsequent offline consolidation. Public Library of Science 2011-11-17 /pmc/articles/PMC3219667/ /pubmed/22114672 http://dx.doi.org/10.1371/journal.pone.0027421 Text en van der Helm et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article van der Helm, Els Gujar, Ninad Nishida, Masaki Walker, Matthew P. Sleep-Dependent Facilitation of Episodic Memory Details |
title | Sleep-Dependent Facilitation of Episodic Memory Details |
title_full | Sleep-Dependent Facilitation of Episodic Memory Details |
title_fullStr | Sleep-Dependent Facilitation of Episodic Memory Details |
title_full_unstemmed | Sleep-Dependent Facilitation of Episodic Memory Details |
title_short | Sleep-Dependent Facilitation of Episodic Memory Details |
title_sort | sleep-dependent facilitation of episodic memory details |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219667/ https://www.ncbi.nlm.nih.gov/pubmed/22114672 http://dx.doi.org/10.1371/journal.pone.0027421 |
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