Cargando…

Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway

BACKGROUND: Cancer stem cells (CSCs) play an important role in cancer initiation, relapse and metastasis. To date, no specific medicine has been found to target CSCs as they are resistant to most conventional therapies and proliferate indefinitely. Compound Kushen Injection (CKI) has been widely use...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Weiru, Lin, Hongsheng, Zhang, Ying, Chen, Xinyi, Hua, Baojin, Hou, Wei, Qi, Xin, Pei, Yingxia, Zhu, Xiaoyun, Zhao, Zhizheng, Yang, Liangliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219673/ https://www.ncbi.nlm.nih.gov/pubmed/22032476 http://dx.doi.org/10.1186/1756-9966-30-103

Ejemplares similares

Effects of compound Kushen injection on pathology and angiogenesis of tumor tissues
por: Wang, Hongyan, et al.
Publicado: (2019)

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis
por: Shen, Hanyuan, et al.
Publicado: (2019)

Mechanisms of Compound Kushen Injection for the Treatment of Lung Cancer Based on Network Pharmacology
por: Meng, Ziqi, et al.
Publicado: (2019)

Compound Kushen injection reduces severity of radiation-induced gastrointestinal mucositis in rats
por: Harata-Lee, Yuka, et al.
Publicado: (2022)

Cell cycle, energy metabolism and DNA repair pathways in cancer cells are suppressed by Compound Kushen Injection
por: Cui, Jian, et al.
Publicado: (2019)

The effect of compound kushen injection on cancer cells: Integrated identification of candidate molecular mechanisms
por: Cui, Jian, et al.
Publicado: (2020)

Compound Kushen Injection for gastric cancer: A protocol of systematic review and meta-analysis
por: Huang, Zhihong, et al.
Publicado: (2019)

Study on the mechanisms of compound Kushen injection for the treatment of gastric cancer based on network pharmacology
por: Zhou, Wei, et al.
Publicado: (2020)

Compound kushen injection for multiple myeloma: A protocol of systematic review and meta-analysis
por: Yang, Xinwei, et al.
Publicado: (2019)

Compound Kushen Injection Protects Skin From Radiation Injury via Regulating Bim
por: Zheng, Jianxiao, et al.
Publicado: (2021)

Antioxidant and Immunity Activities of Fufang Kushen Injection Liquid
por: Zhou, Shen-Kang, et al.
Publicado: (2012)

Identification of candidate anti-cancer molecular mechanisms of Compound Kushen Injection using functional genomics
por: Qu, Zhipeng, et al.
Publicado: (2016)

Cell cycle arrest is an important mechanism of action of compound Kushen injection in the prevention of colorectal cancer
por: Sun, Jie, et al.
Publicado: (2022)

The feasibility of using the compound kushen injection to treat cervical cancer based on network pharmacology and transcriptomics
por: Zhang, Yiting, et al.
Publicado: (2023)

Down-Regulation of the Canonical Wnt β-Catenin Pathway in the Airway Epithelium of Healthy Smokers and Smokers with COPD
por: Wang, Rui, et al.
Publicado: (2011)

Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling
por: Janda, Claudia Y., et al.
Publicado: (2017)

Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway
por: Jin, Yanxia, et al.
Publicado: (2018)

Cannabidiol and the Canonical WNT/β-Catenin Pathway in Glaucoma
por: Vallée, Alexandre, et al.
Publicado: (2021)

Efficacy of Compound Kushen Injection in Relieving Cancer-Related Pain: A Systematic Review and Meta-Analysis
por: Guo, Yu-ming, et al.
Publicado: (2015)

A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer
por: Li, Yi, et al.
Publicado: (2021)

Single-cell RNA-sequencing uncovers compound kushen injection synergistically improves the efficacy of chemotherapy by modulating the tumor environment of breast cancer
por: Liu, Xinkui, et al.
Publicado: (2022)

Aidi Injection, Compound Kushen Injection, or Kanglaite Injection: Which Is the Best Partner with Systemic Chemotherapy for Patients with HCC? A Network Meta-Analysis
por: Dou, Dou, et al.
Publicado: (2020)

Efficacy of Compound Kushen Injection in Combination with Induction Chemotherapy for Treating Adult Patients Newly Diagnosed with Acute Leukemia
por: Tu, Honglei, et al.
Publicado: (2016)

Fractional Deletion of Compound Kushen Injection Indicates Cytokine Signaling Pathways are Critical for its Perturbation of the Cell Cycle
por: Aung, T. N., et al.
Publicado: (2019)

Network Pharmacology-Based Study on the Molecular Biological Mechanism of Action for Compound Kushen Injection in Anti-Cancer Effect
por: He, Ruirong, et al.
Publicado: (2020)

Compound Kushen injection inhibits EMT of gastric cancer cells via the PI3K/AKT pathway
por: Li, Luo, et al.
Publicado: (2022)

Exploring the nucleotide molecular mechanism of compound kushen injection for lung adenocarcinoma based on network pharmacology and molecular docking
por: Ye, Zhangpeng, et al.
Publicado: (2022)

High Throughput Transcriptome Data Analysis and Computational Verification Reveal Immunotherapy Biomarkers of Compound Kushen Injection for Treating Triple-Negative Breast Cancer
por: Liu, Xinkui, et al.
Publicado: (2021)

Targeting the canonical Wnt/β-catenin pathway in hematological malignancies
por: Ashihara, Eishi, et al.
Publicado: (2015)

New Advances in Canonical Wnt/β-Catenin Signaling in Cancer
por: Wen, Xiaolan, et al.
Publicado: (2020)

Multiple Targets of the Canonical WNT/β-Catenin Signaling in Cancers
por: Lecarpentier, Yves, et al.
Publicado: (2019)

KCTD1 Suppresses Canonical Wnt Signaling Pathway by Enhancing β-catenin Degradation
por: Li, Xinxin, et al.
Publicado: (2014)

Effect of Compound Kushen Injection, a Natural Compound Mixture, and Its Identified Chemical Components on Migration and Invasion of Colon, Brain, and Breast Cancer Cell Lines
por: Nourmohammadi, Saeed, et al.
Publicado: (2019)

Efficacy and Safety of Compound Kushen Injection on Patients with Advanced Colon Cancer: A Meta-Analysis of Randomized Controlled Trials
por: Yu, Lixiu, et al.
Publicado: (2017)

Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation
por: Gao, Li, et al.
Publicado: (2018)

Integrated bioinformatics analysis to decipher molecular mechanism of compound Kushen injection for esophageal cancer by combining WGCNA with network pharmacology
por: Zhou, Wei, et al.
Publicado: (2020)

Compound Kushen injection attenuates angiotensin II-mediated heart failure by inhibiting the PI3K/Akt pathway
por: Wang, Wei, et al.
Publicado: (2023)

β-Elemene inhibits the proliferation of primary human airway granulation fibroblasts by down-regulating canonical Wnt/β-catenin pathway
por: Xue, Cheng, et al.
Publicado: (2018)

Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation
por: Hägglund, Anna-Carin, et al.
Publicado: (2013)

The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
por: You, Hongjuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ag4mu9lrj4b9sckam40lut2phg