Inhibition of IL-10 Production by Maternal Antibodies against Group B Streptococcus GAPDH Confers Immunity to Offspring by Favoring Neutrophil Recruitment

Group B Streptococcus (GBS) is the leading cause of neonatal pneumonia, septicemia, and meningitis. We have previously shown that in adult mice GBS glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an extracellular virulence factor that induces production of the immunosuppressive...

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Detalles Bibliográficos
Autores principales: Madureira, Pedro, Andrade, Elva Bonifácio, Gama, Bernardo, Oliveira, Liliana, Moreira, Susana, Ribeiro, Adília, Correia-Neves, Margarida, Trieu-Cuot, Patrick, Vilanova, Manuel, Ferreira, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219712/
https://www.ncbi.nlm.nih.gov/pubmed/22114550
http://dx.doi.org/10.1371/journal.ppat.1002363

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