A TNF-Regulated Recombinatorial Macrophage Immune Receptor Implicated in Granuloma Formation in Tuberculosis

Macrophages play a central role in host defense against mycobacterial infection and anti- TNF therapy is associated with granuloma disorganization and reactivation of tuberculosis in humans. Here, we provide evidence for the presence of a T cell receptor (TCR) αβ based recombinatorial immune recepto...

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Detalles Bibliográficos
Autores principales: Beham, Alexander W., Puellmann, Kerstin, Laird, Rebecca, Fuchs, Tina, Streich, Roswita, Breysach, Caroline, Raddatz, Dirk, Oniga, Septimia, Peccerella, Teresa, Findeisen, Peter, Kzhyshkowska, Julia, Gratchev, Alexei, Schweyer, Stefan, Saunders, Bernadette, Wessels, Johannes T., Möbius, Wiebke, Keane, Joseph, Becker, Heinz, Ganser, Arnold, Neumaier, Michael, Kaminski, Wolfgang E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219713/
https://www.ncbi.nlm.nih.gov/pubmed/22114556
http://dx.doi.org/10.1371/journal.ppat.1002375

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