UDP-glucose 4, 6-dehydratase Activity Plays an Important Role in Maintaining Cell Wall Integrity and Virulence of Candida albicans

Candida albicans, a human fungal pathogen, undergoes morphogenetic changes that are associated with virulence. We report here that GAL102 in C. albicans encodes a homolog of dTDP-glucose 4,6-dehydratase, an enzyme that affects cell wall properties as well as virulence of many pathogenic bacteria. We...

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Detalles Bibliográficos
Autores principales: Sen, Manimala, Shah, Bhavin, Rakshit, Srabanti, Singh, Vijender, Padmanabhan, Bhavna, Ponnusamy, Manikandan, Pari, Koteppa, Vishwakarma, Ram, Nandi, Dipankar, Sadhale, Parag P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219719/
https://www.ncbi.nlm.nih.gov/pubmed/22114559
http://dx.doi.org/10.1371/journal.ppat.1002384

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