Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1

The majority of patients with lung cancer present with metastatic disease. Chronic inflammation and subsequent activation of NF-κB have been associated the development of cancers. The RelA/p65 subunit of NF-κB is typically associated with transcriptional activation. In this report we show that RelA/...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Mayo, Marty W., Nagji, Alykhan S., Smith, Philip W., Ramsey, Catherine S., Li, Duo, Jones, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219802/
https://www.ncbi.nlm.nih.gov/pubmed/21765477
http://dx.doi.org/10.1038/onc.2011.308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219802/
https://www.ncbi.nlm.nih.gov/pubmed/21765477
http://dx.doi.org/10.1038/onc.2011.308

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