ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study

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BACKGROUND: Expression of estrogen receptor alpha (ERα) is predictive for endocrine therapy response and an important prognostic factor in breast cancer. Overexpression of ERα can be caused by estrogen receptor 1 (ESR1) gene amplification and was originally reported to be a frequent event associated...

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Detalles Bibliográficos
Autores principales: Moelans, Cathy B., Monsuur, Hanneke N., de Pinth, Johannes H., Radersma, Remco D., de Weger, Roel A., van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219866/
https://www.ncbi.nlm.nih.gov/pubmed/21541733
http://dx.doi.org/10.1007/s13402-011-0045-5
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