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Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas

BACKGROUND: Transforming growth factor beta (TGF-ß) is able to inhibit the proliferation of epithelial cells and is involved in the carcinogenesis of mammary tumors. Three latent transforming growth factor-ß binding proteins (LTBPs) are known to modulate TGF-ß functions. METHODS: The current study a...

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Detalles Bibliográficos
Autores principales: Kretschmer, Celine, Conradi, Anne, Kemmner, Wolfgang, Sterner-Kock, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219867/
https://www.ncbi.nlm.nih.gov/pubmed/21468687
http://dx.doi.org/10.1007/s13402-011-0023-y