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Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats
INTRODUCTION: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), the major endothelial receptor for oxidized low-density lipoprotein, is also involved in leukocyte recruitment. Systemic leukocyte activation in sepsis represents a crucial factor in the impairment of the microcirculation...
Autores principales: | Landsberger, Martin, Zhou, Juan, Wilk, Sebastian, Thaumüller, Corinna, Pavlovic, Dragan, Otto, Marion, Whynot, Sara, Hung, Orlando, Murphy, Michael F, Cerny, Vladimir, Felix, Stephan B, Lehmann, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220004/ https://www.ncbi.nlm.nih.gov/pubmed/21143965 http://dx.doi.org/10.1186/cc9367 |
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