Cargando…
Increased complexity of vasopressin's vascular actions
Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in con...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220049/ https://www.ncbi.nlm.nih.gov/pubmed/21156084 http://dx.doi.org/10.1186/cc9344 |
_version_ | 1782216938960715776 |
---|---|
author | Landry, Donald W Oliver, Juan A |
author_facet | Landry, Donald W Oliver, Juan A |
author_sort | Landry, Donald W |
collection | PubMed |
description | Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in conflicting effects. In the present issue of Critical Care, Rehberg and colleagues examined the hypothesis that blockade of vasopressin V2 receptor during septic shock may be beneficial. Their tantalizing results indicate that future work must consider the precise vasopressin receptors that are stimulated and/or inhibited. |
format | Online Article Text |
id | pubmed-3220049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-32200492011-12-13 Increased complexity of vasopressin's vascular actions Landry, Donald W Oliver, Juan A Crit Care Commentary Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in conflicting effects. In the present issue of Critical Care, Rehberg and colleagues examined the hypothesis that blockade of vasopressin V2 receptor during septic shock may be beneficial. Their tantalizing results indicate that future work must consider the precise vasopressin receptors that are stimulated and/or inhibited. BioMed Central 2010 2010-12-13 /pmc/articles/PMC3220049/ /pubmed/21156084 http://dx.doi.org/10.1186/cc9344 Text en Copyright ©2010 BioMed Central Ltd |
spellingShingle | Commentary Landry, Donald W Oliver, Juan A Increased complexity of vasopressin's vascular actions |
title | Increased complexity of vasopressin's vascular actions |
title_full | Increased complexity of vasopressin's vascular actions |
title_fullStr | Increased complexity of vasopressin's vascular actions |
title_full_unstemmed | Increased complexity of vasopressin's vascular actions |
title_short | Increased complexity of vasopressin's vascular actions |
title_sort | increased complexity of vasopressin's vascular actions |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220049/ https://www.ncbi.nlm.nih.gov/pubmed/21156084 http://dx.doi.org/10.1186/cc9344 |
work_keys_str_mv | AT landrydonaldw increasedcomplexityofvasopressinsvascularactions AT oliverjuana increasedcomplexityofvasopressinsvascularactions |