Cargando…

Increased complexity of vasopressin's vascular actions

Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in con...

Descripción completa

Detalles Bibliográficos
Autores principales: Landry, Donald W, Oliver, Juan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220049/
https://www.ncbi.nlm.nih.gov/pubmed/21156084
http://dx.doi.org/10.1186/cc9344
_version_ 1782216938960715776
author Landry, Donald W
Oliver, Juan A
author_facet Landry, Donald W
Oliver, Juan A
author_sort Landry, Donald W
collection PubMed
description Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in conflicting effects. In the present issue of Critical Care, Rehberg and colleagues examined the hypothesis that blockade of vasopressin V2 receptor during septic shock may be beneficial. Their tantalizing results indicate that future work must consider the precise vasopressin receptors that are stimulated and/or inhibited.
format Online
Article
Text
id pubmed-3220049
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-32200492011-12-13 Increased complexity of vasopressin's vascular actions Landry, Donald W Oliver, Juan A Crit Care Commentary Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in conflicting effects. In the present issue of Critical Care, Rehberg and colleagues examined the hypothesis that blockade of vasopressin V2 receptor during septic shock may be beneficial. Their tantalizing results indicate that future work must consider the precise vasopressin receptors that are stimulated and/or inhibited. BioMed Central 2010 2010-12-13 /pmc/articles/PMC3220049/ /pubmed/21156084 http://dx.doi.org/10.1186/cc9344 Text en Copyright ©2010 BioMed Central Ltd
spellingShingle Commentary
Landry, Donald W
Oliver, Juan A
Increased complexity of vasopressin's vascular actions
title Increased complexity of vasopressin's vascular actions
title_full Increased complexity of vasopressin's vascular actions
title_fullStr Increased complexity of vasopressin's vascular actions
title_full_unstemmed Increased complexity of vasopressin's vascular actions
title_short Increased complexity of vasopressin's vascular actions
title_sort increased complexity of vasopressin's vascular actions
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220049/
https://www.ncbi.nlm.nih.gov/pubmed/21156084
http://dx.doi.org/10.1186/cc9344
work_keys_str_mv AT landrydonaldw increasedcomplexityofvasopressinsvascularactions
AT oliverjuana increasedcomplexityofvasopressinsvascularactions