Surface Architecture of Histoplasma Capsulatum

The dimorphic fungal pathogen Histoplasma capsulatum is the most frequent cause of clinically significant fungal pneumonia in humans. H. capsulatum virulence is achieved, in part, through diverse and dynamic alterations to the fungal cell surface. Surface components associated with H. capsulatum pat...

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Detalles Bibliográficos
Autores principales: Guimarães, Allan J., de Cerqueira, Mariana D., Nosanchuk, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220077/
https://www.ncbi.nlm.nih.gov/pubmed/22121356
http://dx.doi.org/10.3389/fmicb.2011.00225
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author Guimarães, Allan J.
de Cerqueira, Mariana D.
Nosanchuk, Joshua D.
author_facet Guimarães, Allan J.
de Cerqueira, Mariana D.
Nosanchuk, Joshua D.
author_sort Guimarães, Allan J.
collection PubMed
description The dimorphic fungal pathogen Histoplasma capsulatum is the most frequent cause of clinically significant fungal pneumonia in humans. H. capsulatum virulence is achieved, in part, through diverse and dynamic alterations to the fungal cell surface. Surface components associated with H. capsulatum pathogenicity include carbohydrates, lipids, proteins, and melanins. Here, we describe the various structures comprising the cell surface of H. capsulatum that have been associated with virulence and discuss their involvement in the pathobiology of disease.
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spelling pubmed-32200772011-11-25 Surface Architecture of Histoplasma Capsulatum Guimarães, Allan J. de Cerqueira, Mariana D. Nosanchuk, Joshua D. Front Microbiol Microbiology The dimorphic fungal pathogen Histoplasma capsulatum is the most frequent cause of clinically significant fungal pneumonia in humans. H. capsulatum virulence is achieved, in part, through diverse and dynamic alterations to the fungal cell surface. Surface components associated with H. capsulatum pathogenicity include carbohydrates, lipids, proteins, and melanins. Here, we describe the various structures comprising the cell surface of H. capsulatum that have been associated with virulence and discuss their involvement in the pathobiology of disease. Frontiers Research Foundation 2011-11-18 /pmc/articles/PMC3220077/ /pubmed/22121356 http://dx.doi.org/10.3389/fmicb.2011.00225 Text en Copyright © 2011 Guimarães, de Cerqueira and Nosanchuk. http://www.frontiersin.org/licenseagreement This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.
spellingShingle Microbiology
Guimarães, Allan J.
de Cerqueira, Mariana D.
Nosanchuk, Joshua D.
Surface Architecture of Histoplasma Capsulatum
title Surface Architecture of Histoplasma Capsulatum
title_full Surface Architecture of Histoplasma Capsulatum
title_fullStr Surface Architecture of Histoplasma Capsulatum
title_full_unstemmed Surface Architecture of Histoplasma Capsulatum
title_short Surface Architecture of Histoplasma Capsulatum
title_sort surface architecture of histoplasma capsulatum
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220077/
https://www.ncbi.nlm.nih.gov/pubmed/22121356
http://dx.doi.org/10.3389/fmicb.2011.00225
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AT decerqueiramarianad surfacearchitectureofhistoplasmacapsulatum
AT nosanchukjoshuad surfacearchitectureofhistoplasmacapsulatum

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