Cargando…
A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function
[Image: see text] Proteases constitute a major class of drug targets. Endosomal compartments harbor several protease families whose attenuation may be beneficial to a number of biological processes, including inflammation, cancer metastasis, antigen presentation, and parasite clearance. As a step to...
Autores principales: | van Kasteren, Sander I., Berlin, Ilana, Colbert, Jeff D., Keane, Doreen, Ovaa, Huib, Watts, Colin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2011
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220280/ https://www.ncbi.nlm.nih.gov/pubmed/21910425 http://dx.doi.org/10.1021/cb200292c |
Ejemplares similares
-
On Terminal Alkynes That
Can React with Active-Site
Cysteine Nucleophiles in Proteases
por: Ekkebus, Reggy, et al.
Publicado: (2013) -
Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis
por: Hamilton, Garth, et al.
Publicado: (2008) -
Ubiquitin and its relatives as wizards of the endolysosomal system
por: Berlin, Ilana, et al.
Publicado: (2023) -
Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion
por: McDonald, Christian, et al.
Publicado: (2020) -
Total Chemical Synthesis of SUMO and SUMO‐Based Probes for Profiling the Activity of SUMO‐Specific Proteases
por: Mulder, Monique P. C., et al.
Publicado: (2018)