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Interactions between Naïve and Infected Macrophages Reduce Mycobacterium tuberculosis Viability

A high intracellular bacillary load of Mycobacterium tuberculosis in macrophages induces an atypical lysosomal cell death with early features of apoptosis that progress to necrosis within hours. Unlike classical apoptosis, this cell death mode does not appear to diminish M. tuberculosis viability. W...

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Detalles Bibliográficos
Autores principales: Hartman, Michelle L., Kornfeld, Hardy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220711/
https://www.ncbi.nlm.nih.gov/pubmed/22125644
http://dx.doi.org/10.1371/journal.pone.0027972

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