SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA

All-trans retinoic acid (ATRA) induces complete remission in most cases of acute promyelocytic leukemia. Toxicity of ATRA has been shown to be mild, consisting of headache, dry skin, dermatitis, and gastrointestinal disorders. We describe a case of scrotal ulceration with ATRA use in a Moroccan pati...

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Autores principales: Tazi, Illias, Rachid, Mohamed, Quessar, Asmaa, Benchekroun, Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221224/
https://www.ncbi.nlm.nih.gov/pubmed/22121279
http://dx.doi.org/10.4103/0019-5154.87156
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author Tazi, Illias
Rachid, Mohamed
Quessar, Asmaa
Benchekroun, Said
author_facet Tazi, Illias
Rachid, Mohamed
Quessar, Asmaa
Benchekroun, Said
author_sort Tazi, Illias
collection PubMed
description All-trans retinoic acid (ATRA) induces complete remission in most cases of acute promyelocytic leukemia. Toxicity of ATRA has been shown to be mild, consisting of headache, dry skin, dermatitis, and gastrointestinal disorders. We describe a case of scrotal ulceration with ATRA use in a Moroccan patient, an occurrence that has been rarely reported in the medical literature. The pathogenesis of scrotal ulceration remains unknown. Our experience indicates the importance of recognizing genital ulcers associated with ATRA in order that appropriate countermeasures can be taken.
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spelling pubmed-32212242011-11-25 SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA Tazi, Illias Rachid, Mohamed Quessar, Asmaa Benchekroun, Said Indian J Dermatol Case Report All-trans retinoic acid (ATRA) induces complete remission in most cases of acute promyelocytic leukemia. Toxicity of ATRA has been shown to be mild, consisting of headache, dry skin, dermatitis, and gastrointestinal disorders. We describe a case of scrotal ulceration with ATRA use in a Moroccan patient, an occurrence that has been rarely reported in the medical literature. The pathogenesis of scrotal ulceration remains unknown. Our experience indicates the importance of recognizing genital ulcers associated with ATRA in order that appropriate countermeasures can be taken. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3221224/ /pubmed/22121279 http://dx.doi.org/10.4103/0019-5154.87156 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tazi, Illias
Rachid, Mohamed
Quessar, Asmaa
Benchekroun, Said
SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA
title SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA
title_full SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA
title_fullStr SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA
title_full_unstemmed SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA
title_short SCROTAL ULCERATION FOLLOWING ALL-TRANS RETINOIC ACID THERAPY FOR ACUTE PROMYELOCYTIC LEUKEMIA
title_sort scrotal ulceration following all-trans retinoic acid therapy for acute promyelocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221224/
https://www.ncbi.nlm.nih.gov/pubmed/22121279
http://dx.doi.org/10.4103/0019-5154.87156
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