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SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE

We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurat...

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Autores principales: Madke, Bhushan, Kharkar, Vidya, Chikhalkar, Siddhi, Mahajan, Sunanda, Khopkar, Uday
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221233/
https://www.ncbi.nlm.nih.gov/pubmed/22121288
http://dx.doi.org/10.4103/0019-5154.87165
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author Madke, Bhushan
Kharkar, Vidya
Chikhalkar, Siddhi
Mahajan, Sunanda
Khopkar, Uday
author_facet Madke, Bhushan
Kharkar, Vidya
Chikhalkar, Siddhi
Mahajan, Sunanda
Khopkar, Uday
author_sort Madke, Bhushan
collection PubMed
description We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy.
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spelling pubmed-32212332011-11-25 SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE Madke, Bhushan Kharkar, Vidya Chikhalkar, Siddhi Mahajan, Sunanda Khopkar, Uday Indian J Dermatol Case Report We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3221233/ /pubmed/22121288 http://dx.doi.org/10.4103/0019-5154.87165 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Madke, Bhushan
Kharkar, Vidya
Chikhalkar, Siddhi
Mahajan, Sunanda
Khopkar, Uday
SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_full SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_fullStr SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_full_unstemmed SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_short SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_sort successful treatment of multifocal cutaneous leishmaniasis with miltefosine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221233/
https://www.ncbi.nlm.nih.gov/pubmed/22121288
http://dx.doi.org/10.4103/0019-5154.87165
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