Cargando…
SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurat...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221233/ https://www.ncbi.nlm.nih.gov/pubmed/22121288 http://dx.doi.org/10.4103/0019-5154.87165 |
_version_ | 1782217064738455552 |
---|---|
author | Madke, Bhushan Kharkar, Vidya Chikhalkar, Siddhi Mahajan, Sunanda Khopkar, Uday |
author_facet | Madke, Bhushan Kharkar, Vidya Chikhalkar, Siddhi Mahajan, Sunanda Khopkar, Uday |
author_sort | Madke, Bhushan |
collection | PubMed |
description | We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy. |
format | Online Article Text |
id | pubmed-3221233 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-32212332011-11-25 SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE Madke, Bhushan Kharkar, Vidya Chikhalkar, Siddhi Mahajan, Sunanda Khopkar, Uday Indian J Dermatol Case Report We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3221233/ /pubmed/22121288 http://dx.doi.org/10.4103/0019-5154.87165 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Madke, Bhushan Kharkar, Vidya Chikhalkar, Siddhi Mahajan, Sunanda Khopkar, Uday SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE |
title | SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE |
title_full | SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE |
title_fullStr | SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE |
title_full_unstemmed | SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE |
title_short | SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE |
title_sort | successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221233/ https://www.ncbi.nlm.nih.gov/pubmed/22121288 http://dx.doi.org/10.4103/0019-5154.87165 |
work_keys_str_mv | AT madkebhushan successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT kharkarvidya successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT chikhalkarsiddhi successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT mahajansunanda successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT khopkaruday successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine |