Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

MicroRNAs (miRNAs) interact with 3′-untranslated regions of messenger RNAs to restrict expression of most protein-coding genes during normal development and cancer. RNA-binding proteins (RBPs) can control the biogenesis, stability and activity of miRNAs. Here we identify RBM38 in a genetic screen fo...

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Detalles Bibliográficos
Autores principales: Léveillé, Nicolas, Elkon, Ran, Davalos, Veronica, Manoharan, Vijayalaxmi, Hollingworth, Dave, Vrielink, Joachim Oude, le Sage, Carlos, Melo, Carlos A., Horlings, Hugo M., Wesseling, Jelle, Ule, Jernej, Esteller, Manel, Ramos, Andres, Agami, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221330/
https://www.ncbi.nlm.nih.gov/pubmed/22027593
http://dx.doi.org/10.1038/ncomms1519

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