Cargando…

Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer

Background: Lapatinib (GW572016) is a dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2/ErbB2), which are reported as overexpressed in 15%–45% of gastric cancers, making them potential targets. Patients and methods: The prima...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iqbal, S., Goldman, B., Fenoglio-Preiser, C. M., Lenz, H. J., Zhang, W., Danenberg, K. D., Shibata, S. I., Blanke, C. D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221514/ https://www.ncbi.nlm.nih.gov/pubmed/21415234 http://dx.doi.org/10.1093/annonc/mdr021

Ejemplares similares

Evaluation of Anti-inflammatory and Antimicrobial Activity of AHPL/AYCAP/0413 Capsule
por: Nipanikar, Sanjay, et al.
Publicado: (2017)

Clinical and dosimetric experience with MammoSite‐based brachytherapy under the RTOG 0413 protocol
por: Wojcicka, Jadwiga B., et al.
Publicado: (2007)

Metastatic squamous cell carcinoma of the skin with clinical response to lapatinib
por: Strickley, John D., et al.
Publicado: (2018)

P04.13. Population-based case-control study of Chinese herbal products containing ephedra and cardiovascular disease risk
por: Lin, Y, et al.
Publicado: (2012)

P.0413 Modifiable risk and protective factors influencing changes in subjective depression during the COVID-19-lockdown: identifying targets for prevention and intervention
por: Elek, L.P., et al.
Publicado: (2021)

GW Stewart
por: Kilmer, Misha E, et al.
Publicado: (2010)

Association of Diet Quality With Survival Among People With Metastatic Colorectal Cancer in the Cancer and Leukemia B and Southwest Oncology Group 80405 Trial
por: Van Blarigan, Erin L., et al.
Publicado: (2020)

Q-TWiST analysis of lapatinib combined with capecitabine for the treatment of metastatic breast cancer
por: Sherrill, B, et al.
Publicado: (2008)

Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases – the UK experience
por: Sutherland, S, et al.
Publicado: (2010)

Lapatinib: the evidence for its therapeutic value in metastatic breast cancer
por: Thomson, Andrew
Publicado: (2005)

Programming in GW-BASIC
por: McBride, P K
Publicado: (1991)

Role of lapatinib in the first-line treatment of patients with metastatic breast cancer
por: Oakman, Catherine, et al.
Publicado: (2010)

Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer()()
por: Zhang, Lixin, et al.
Publicado: (2015)

Coalescence of Kerr Black Holes—Binary Systems from GW150914 to GW170814
por: Gwak, Bogeun
Publicado: (2019)

Workshop on GW Data Analysis
Publicado: (1997)

Instant MinGW starter
por: Shpigor, Ilya
Publicado: (2013)

Metastatic, Her-2 Amplified Lacrimal Gland Carcinoma with Response to Lapatinib Treatment
por: Dennie, Trevor
Publicado: (2015)

The Efficacy of Pyrotinib as a Third- or Higher-Line Treatment in HER2-Positive Metastatic Breast Cancer Patients Exposed to Lapatinib Compared to Lapatinib-Naive Patients: A Real-World Study
por: Ouyang, D. J, et al.
Publicado: (2021)

The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression
por: Chekulaeva, Marina, et al.
Publicado: (2010)

Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC
por: Castilla-Llorente, Virginia, et al.
Publicado: (2012)

Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer
por: Yi, Huixing, et al.
Publicado: (2021)

Real‐world data of lapatinib and treatment after lapatinib in patients with previously treated HER2‐positive metastatic breast cancer: A multicenter, retrospective study
por: Xie, Yizhao, et al.
Publicado: (2020)

GW-BASIC a su alcance
por: Albrecht, Bob, 1930-
Publicado: (1990)

What is the source of the PTA GW signal?
por: Ellis, John, et al.
Publicado: (2023)

The GW/BSE Method in Magnetic Fields
por: Holzer, Christof, et al.
Publicado: (2021)

Dual HER2 blockade with lapatinib and trastuzumab in combination with chemotherapy in metastatic gastroesophageal adenocarcinoma
por: Cheong, E. Von, et al.
Publicado: (2021)

A randomized phase II study of lapatinib + pazopanib versus lapatinib in patients with HER2+ inflammatory breast cancer
por: Cristofanilli, Massimo, et al.
Publicado: (2012)

Randomised Phase 2 study of lapatinib and vinorelbine vs vinorelbine in patients with HER2 + metastatic breast cancer after lapatinib and trastuzumab treatment (KCSG BR11-16)
por: Sim, Sung Hoon, et al.
Publicado: (2019)

Lapatinib-induced acute generalized exanthematous pustulosis
por: Lakshmi, Chembolli, et al.
Publicado: (2010)

GW body disassembly triggered by siRNAs independently of their silencing activity
por: Serman, A., et al.
Publicado: (2007)

PPAR-γ Agonist GW1929 But Not Antagonist GW9662 Reduces TBBPA-Induced Neurotoxicity in Primary Neocortical Cells
por: Wojtowicz, Anna K., et al.
Publicado: (2013)

Two-Component GW Calculations: Cubic Scaling Implementation and Comparison of Vertex-Corrected and Partially Self-Consistent GW Variants
por: Förster, Arno, et al.
Publicado: (2023)

A phase II study of lapatinib and bevacizumab as treatment for HER2-overexpressing metastatic breast cancer
por: Rugo, Hope S., et al.
Publicado: (2011)

An open-label, pilot study of veliparib and lapatinib in patients with metastatic, triple-negative breast cancer
por: Stringer-Reasor, Erica M., et al.
Publicado: (2021)

Comments on Graviton Propagation in Light of GW150914
por: Ellis, John, et al.
Publicado: (2016)

Primordial Magnetic Fields and Stochastic GW backgrounds
por: Giovannini, Massimo
Publicado: (2002)

discussion: next steps for UHF GW initiative
por: CERN. Geneva
Publicado: (2021)

GW experiments for dark matter direct detection
por: Zhao, Yue
Publicado: (2021)

UHF-GW solid state detector proposal
por: Garcia-Bellido Capdevila, Juan
Publicado: (2021)

Stochastic GW backgrounds from astrophysical sources
por: Dvorkin, Irina
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n05ncubn8ijtlongqcikjep8ic