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Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability
BACKGROUND: Genetic risk models could potentially be useful in identifying high-risk groups for the prevention of complex diseases. We investigated the performance of this risk stratification strategy by examining epidemiological parameters that impact the predictive ability of risk models. METHODS:...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221548/ https://www.ncbi.nlm.nih.gov/pubmed/21797996 http://dx.doi.org/10.1186/gm267 |