Cargando…

Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series

Uveitis treatment involves topical corticosteroids along with cycloplegic-mydriatics. Particularly severe cases may require systemic corticosteroids and immunosuppressive drugs. Vernal keratoconjunctivitis (VKC) treatment consists of a brief period of topical corticosteroids and/or cyclosporine. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Taddio, Andrea, Cimaz, Rolando, Caputo, Roberto, de Libero, Cinzia, Di Grande, Laura, Simonini, Gabriele, Mori, Francesca, Novembre, Elio, Pucci, Neri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221618/
https://www.ncbi.nlm.nih.gov/pubmed/22047067
http://dx.doi.org/10.1186/1546-0096-9-34
_version_ 1782217110238265344
author Taddio, Andrea
Cimaz, Rolando
Caputo, Roberto
de Libero, Cinzia
Di Grande, Laura
Simonini, Gabriele
Mori, Francesca
Novembre, Elio
Pucci, Neri
author_facet Taddio, Andrea
Cimaz, Rolando
Caputo, Roberto
de Libero, Cinzia
Di Grande, Laura
Simonini, Gabriele
Mori, Francesca
Novembre, Elio
Pucci, Neri
author_sort Taddio, Andrea
collection PubMed
description Uveitis treatment involves topical corticosteroids along with cycloplegic-mydriatics. Particularly severe cases may require systemic corticosteroids and immunosuppressive drugs. Vernal keratoconjunctivitis (VKC) treatment consists of a brief period of topical corticosteroids and/or cyclosporine. In patients refractory to traditional treatment, the use of 0.1% topical ophtalmic FK- 506 (tacrolimus) ointment has been occasionally reported. This is the first report of the coexistence of uveitis and VKC. The documented response to topical tacrolimus eyedrop of uveitis and VKC is also of interest, in particular since to our knowledge there are no published reports on its clinical use in uveitis.
format Online
Article
Text
id pubmed-3221618
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-32216182011-11-22 Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series Taddio, Andrea Cimaz, Rolando Caputo, Roberto de Libero, Cinzia Di Grande, Laura Simonini, Gabriele Mori, Francesca Novembre, Elio Pucci, Neri Pediatr Rheumatol Online J Case Report Uveitis treatment involves topical corticosteroids along with cycloplegic-mydriatics. Particularly severe cases may require systemic corticosteroids and immunosuppressive drugs. Vernal keratoconjunctivitis (VKC) treatment consists of a brief period of topical corticosteroids and/or cyclosporine. In patients refractory to traditional treatment, the use of 0.1% topical ophtalmic FK- 506 (tacrolimus) ointment has been occasionally reported. This is the first report of the coexistence of uveitis and VKC. The documented response to topical tacrolimus eyedrop of uveitis and VKC is also of interest, in particular since to our knowledge there are no published reports on its clinical use in uveitis. BioMed Central 2011-11-02 /pmc/articles/PMC3221618/ /pubmed/22047067 http://dx.doi.org/10.1186/1546-0096-9-34 Text en Copyright ©2011 Taddio et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Taddio, Andrea
Cimaz, Rolando
Caputo, Roberto
de Libero, Cinzia
Di Grande, Laura
Simonini, Gabriele
Mori, Francesca
Novembre, Elio
Pucci, Neri
Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series
title Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series
title_full Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series
title_fullStr Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series
title_full_unstemmed Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series
title_short Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series
title_sort childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (vkc): successful treatment with topical tacrolimus. case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221618/
https://www.ncbi.nlm.nih.gov/pubmed/22047067
http://dx.doi.org/10.1186/1546-0096-9-34
work_keys_str_mv AT taddioandrea childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT cimazrolando childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT caputoroberto childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT deliberocinzia childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT digrandelaura childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT simoninigabriele childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT morifrancesca childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT novembreelio childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries
AT puccineri childhoodchronicanterioruveitisassociatedwithvernalkeratoconjunctivitisvkcsuccessfultreatmentwithtopicaltacrolimuscaseseries