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The new platinum-based anticancer agent LA-12 induces retinol binding protein 4 in vivo

BACKGROUND: The initial pharmacokinetic study of a new anticancer agent (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum (IV) (LA-12) was complemented by proteomic screening of rat plasma. The objective of the study was to identify new LA-12 target proteins that serve as markers of LA-...

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Detalles Bibliográficos
Autores principales:	Bouchal, Pavel, Jarkovsky, Jiri, Hrazdilova, Kristyna, Dvorakova, Monika, Struharova, Iva, Hernychova, Lenka, Damborsky, Jiri, Sova, Petr, Vojtesek, Borivoj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221626/ https://www.ncbi.nlm.nih.gov/pubmed/22040120 http://dx.doi.org/10.1186/1477-5956-9-68

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