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Activation of Ras Requires the ERM-Dependent Link of Actin to the Plasma Membrane

BACKGROUND: Receptor tyrosine kinases (RTKs) participate in a multitude of signaling pathways, some of them via the small G-protein Ras. An important component in the activation of Ras is Son of sevenless (SOS), which catalyzes the nucleotide exchange on Ras. PRINCIPAL FINDINGS: We can now demonstra...

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Detalles Bibliográficos
Autores principales:	Sperka, Tobias, Geißler, Katja J., Merkel, Ulrike, Scholl, Ingmar, Rubio, Ignacio, Herrlich, Peter, Morrison, Helen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221661/ https://www.ncbi.nlm.nih.gov/pubmed/22132106 http://dx.doi.org/10.1371/journal.pone.0027511

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