Cargando…

The microRNA-Processing Enzyme Dicer Is Essential for Thyroid Function

Dicer is a type III ribonuclease required for the biogenesis of microRNAs (miRNAs), a class of small non-coding RNAs regulating gene expression at the post-transcriptional level. To explore the functional role of miRNAs in thyroid gland function, we generated a thyrocyte-specific Dicer conditional k...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frezzetti, Daniela, Reale, Carla, Calì, Gaetano, Nitsch, Lucio, Fagman, Henrik, Nilsson, Ola, Scarfò, Marzia, De Vita, Gabriella, Di Lauro, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221669/ https://www.ncbi.nlm.nih.gov/pubmed/22132122 http://dx.doi.org/10.1371/journal.pone.0027648

Ejemplares similares

Selective Dicer Suppression in the Kidney Alters GSK3β/β-Catenin Pathways Promoting a Glomerulocystic Disease
por: Iervolino, Anna, et al.
Publicado: (2015)

In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1
por: Silberschmidt, Daniel, et al.
Publicado: (2011)

Erratum to: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1
por: Silberschmidt, Daniel, et al.
Publicado: (2016)

The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activities
por: Kurzynska-Kokorniak, Anna, et al.
Publicado: (2015)

Dicer-like Enzymes with Sequence Cleavage Preferences
por: Hoehener, Cristina, et al.
Publicado: (2018)

MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer
por: Johanson, Timothy M., et al.
Publicado: (2013)

Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning
por: Fagman, Henrik, et al.
Publicado: (2011)

Deletion of the RNaseIII Enzyme Dicer in Thyroid Follicular Cells Causes Hypothyroidism with Signs of Neoplastic Alterations
por: Rodriguez, Wendy, et al.
Publicado: (2012)

A branching morphogenesis program governs embryonic growth of the thyroid gland
por: Liang, Shawn, et al.
Publicado: (2018)

Asynchrony of Apical Polarization, Luminogenesis, and Functional Differentiation in the Developing Thyroid Gland
por: Johansson, Ellen, et al.
Publicado: (2021)

Biocomputational Characterization and Evolutionary Analysis of Bubaline Dicer1 Enzyme
por: Singh, Jasdeep, et al.
Publicado: (2015)

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
por: Cobb, Bradley S., et al.
Publicado: (2005)

DICER1 Is Essential for Self-Renewal of Human Embryonic Stem Cells
por: Teijeiro, Virginia, et al.
Publicado: (2018)

GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours
por: Paulsson, Johan O, et al.
Publicado: (2020)

Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness
por: Ramírez-Moya, Julia, et al.
Publicado: (2019)

MicroRNA processing without Dicer
por: Dueck, Anne, et al.
Publicado: (2010)

DICER1 Syndrome: DICER1 Mutations in Rare Cancers
por: Robertson, Jake C., et al.
Publicado: (2018)

Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies
por: Theotoki, Eleni I., et al.
Publicado: (2020)

DICER-ARGONAUTE2 Complex in Continuous Fluorogenic Assays of RNA Interference Enzymes
por: Bernard, Mark A., et al.
Publicado: (2015)

Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males
por: Modzelewski, Andrew J., et al.
Publicado: (2015)

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor
por: Schoultz, Elin, et al.
Publicado: (2023)

A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice
por: Mang, Géraldine M., et al.
Publicado: (2015)

The paradox of dicer in cancer
por: Swahari, Vijay, et al.
Publicado: (2016)

Shaping chromatin with DICER
por: Chitale, Shalaka, et al.
Publicado: (2017)

SILAC-Based Quantitative Proteomic Analysis of Diffuse Large B-Cell Lymphoma Patients
por: Rüetschi, Ulla, et al.
Publicado: (2015)

Global Switch from DICER-dependent MicroRNA to DICER-independent SnoRNA-derived RNA Biogenesis in Malignancy
por: Godang, Noel L, et al.
Publicado: (2023)

Dicer and microRNAs protect adult dopamine neurons
por: Chmielarz, Piotr, et al.
Publicado: (2017)

DICER1 Syndrome in Twins With Ovarian Sertoli-Leydig Cell Tumor and Papillary Thyroid Carcinoma
por: Al Hussaini, Hessah A, et al.
Publicado: (2023)

Deregulation of dicer and mir-155 expression in liposarcoma
por: Vincenzi, Bruno, et al.
Publicado: (2015)

The Molecular Architecture of Human Dicer
por: Lau, Pick-Wei, et al.
Publicado: (2012)

Dicer Functions in Aquatic Species
por: Kitagishi, Yasuko, et al.
Publicado: (2011)

DICERing macrophages for reprogramming TAMs
por: Squadrito, Mario Leonardo, et al.
Publicado: (2016)

Zika Says No Dice to Dicer
por: Tang, Hengli
Publicado: (2020)

DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma
por: Doros, Leslie A, et al.
Publicado: (2014)

Reclassification of two germline DICER1 splicing variants leads to DICER1 syndrome diagnosis
por: Apellaniz-Ruiz, Maria, et al.
Publicado: (2023)

The Role of Dicer Protein Partners in the Processing of MicroRNA Precursors
por: Koscianska, Edyta, et al.
Publicado: (2011)

Derivation and characterization of Dicer- and microRNA-deficient human cells
por: Bogerd, Hal P., et al.
Publicado: (2014)

Conservation of Differential Animal MicroRNA Processing by Drosha and Dicer
por: Zhang, Xiaoxiao, et al.
Publicado: (2022)

Structural and functional basis of mammalian microRNA biogenesis by Dicer
por: Zapletal, David, et al.
Publicado: (2022)

DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions
por: Poma, Anello Marcello, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_224u7gs2enlfa8g29llk51gb83