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DNA Methylation Profiles of Primary Colorectal Carcinoma and Matched Liver Metastasis
BACKGROUND: The contribution of DNA methylation to the metastatic process in colorectal cancers (CRCs) is unclear. METHODS: We evaluated the methylation status of 13 genes (MINT1, MINT2, MINT31, MLH1, p16, p14, TIMP3, CDH1, CDH13, THBS1, MGMT, HPP1 and ERα) by bisulfite-pyrosequencing in 79 CRCs com...
Autores principales: | Konishi, Kazuo, Watanabe, Yoshiyuki, Shen, Lanlan, Guo, Yi, Castoro, Ryan J., Kondo, Kimie, Chung, Woonbok, Ahmed, Saira, Jelinek, Jaroslav, Boumber, Yanis A., Estecio, Marcos R., Maegawa, Shinji, Kondo, Yutaka, Itoh, Fumio, Imawari, Michio, Hamilton, Stanley R., Issa, Jean-Pierre J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221680/ https://www.ncbi.nlm.nih.gov/pubmed/22132162 http://dx.doi.org/10.1371/journal.pone.0027889 |
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