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Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010
In China H3N2 and H1N1 swine influenza viruses have been circulating for many years. In January 2010, before swine were infected with foot and mouth disease in Guangdong, some pigs have shown flu-like symptoms: cough, sneeze, runny nose and fever. We collected the nasopharyngeal swab of all sick pig...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221723/ https://www.ncbi.nlm.nih.gov/pubmed/21995516 http://dx.doi.org/10.1186/1743-422X-8-469 |
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author | Kong, Wei Li Huang, Liang Zong Qi, Hai Tao Cao, Nan Zhang, Liang Quan Wang, Heng Guan, Shang Song Qi, Wen Bao Jiao, Pei Rong Liao, Ming Zhang, Gui Hong |
author_facet | Kong, Wei Li Huang, Liang Zong Qi, Hai Tao Cao, Nan Zhang, Liang Quan Wang, Heng Guan, Shang Song Qi, Wen Bao Jiao, Pei Rong Liao, Ming Zhang, Gui Hong |
author_sort | Kong, Wei Li |
collection | PubMed |
description | In China H3N2 and H1N1 swine influenza viruses have been circulating for many years. In January 2010, before swine were infected with foot and mouth disease in Guangdong, some pigs have shown flu-like symptoms: cough, sneeze, runny nose and fever. We collected the nasopharyngeal swab of all sick pigs as much as possible. One subtype H1N2 influenza viruses were isolated from the pig population. The complete genome of one isolate, designated A/swine/Guangdong/1/2010(H1N2), was sequenced and compared with sequences available in GenBank. The nucleotide sequences of all eight viral RNA segments were determined, and then phylogenetic analysis was performed using the neighbor-joining method. HA, NP, M and NS were shown to be closely to swine origin. PB2 and PA were close to avian origin, but NA and PB1were close to human origin. It is a result of a multiple reassortment event. In conclusion, our finding provides further evidence about the interspecies transmission of avian influenza viruses to pigs and emphasizes the importance of reinforcing swine influenza virus (SIV) surveillance, especially before the emergence of highly pathogenic FMDs in pigs in Guangdong. |
format | Online Article Text |
id | pubmed-3221723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-32217232011-11-22 Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 Kong, Wei Li Huang, Liang Zong Qi, Hai Tao Cao, Nan Zhang, Liang Quan Wang, Heng Guan, Shang Song Qi, Wen Bao Jiao, Pei Rong Liao, Ming Zhang, Gui Hong Virol J Short Report In China H3N2 and H1N1 swine influenza viruses have been circulating for many years. In January 2010, before swine were infected with foot and mouth disease in Guangdong, some pigs have shown flu-like symptoms: cough, sneeze, runny nose and fever. We collected the nasopharyngeal swab of all sick pigs as much as possible. One subtype H1N2 influenza viruses were isolated from the pig population. The complete genome of one isolate, designated A/swine/Guangdong/1/2010(H1N2), was sequenced and compared with sequences available in GenBank. The nucleotide sequences of all eight viral RNA segments were determined, and then phylogenetic analysis was performed using the neighbor-joining method. HA, NP, M and NS were shown to be closely to swine origin. PB2 and PA were close to avian origin, but NA and PB1were close to human origin. It is a result of a multiple reassortment event. In conclusion, our finding provides further evidence about the interspecies transmission of avian influenza viruses to pigs and emphasizes the importance of reinforcing swine influenza virus (SIV) surveillance, especially before the emergence of highly pathogenic FMDs in pigs in Guangdong. BioMed Central 2011-10-13 /pmc/articles/PMC3221723/ /pubmed/21995516 http://dx.doi.org/10.1186/1743-422X-8-469 Text en Copyright ©2011 Kong et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Report Kong, Wei Li Huang, Liang Zong Qi, Hai Tao Cao, Nan Zhang, Liang Quan Wang, Heng Guan, Shang Song Qi, Wen Bao Jiao, Pei Rong Liao, Ming Zhang, Gui Hong Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 |
title | Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 |
title_full | Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 |
title_fullStr | Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 |
title_full_unstemmed | Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 |
title_short | Genetic characterization of H1N2 influenza a virus isolated from sick pigs in Southern China in 2010 |
title_sort | genetic characterization of h1n2 influenza a virus isolated from sick pigs in southern china in 2010 |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221723/ https://www.ncbi.nlm.nih.gov/pubmed/21995516 http://dx.doi.org/10.1186/1743-422X-8-469 |
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