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Oxidation of DJ-1 Induced by 6-Hydroxydopamine Decreasing Intracellular Glutathione
DJ-1, the causative gene of a familial form of Parkinson's disease (PD), has been reported to undergo preferential oxidation of the cysteine residue at position 106 (Cys-106) under oxidative stress; however, details of the molecular mechanisms are not well known. In the present study, mechanism...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221727/ https://www.ncbi.nlm.nih.gov/pubmed/22132160 http://dx.doi.org/10.1371/journal.pone.0027883 |