Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients

BACKGROUND: The adaptation of pathogenic fungi to the host environment via large-scale genomic changes is a poorly characterized phenomenon. Cryptococcus neoformans is the leading cause of fungal meningoencephalitis in HIV/AIDS patients, and we recently discovered clinical strains of the fungus that...

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Detalles Bibliográficos
Autores principales: Hu, Guanggan, Wang, Joyce, Choi, Jaehyuk, Jung, Won Hee, Liu, Iris, Litvintseva, Anastasia P, Bicanic, Tihana, Aurora, Rajeev, Mitchell, Thomas G, Perfect, John R, Kronstad, James W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221739/
https://www.ncbi.nlm.nih.gov/pubmed/22032296
http://dx.doi.org/10.1186/1471-2164-12-526

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