Cargando…

tRNA structural and functional changes induced by oxidative stress

Oxidatively damaged biomolecules impair cellular functions and contribute to the pathology of a variety of diseases. RNA is also attacked by reactive oxygen species, and oxidized RNA is increasingly recognized as an important contributor to neurodegenerative complications in humans. Recently, eviden...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nawrot, Barbara, Sochacka, Elzbieta, Düchler, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Birkhäuser Verlag Basel 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221842/ https://www.ncbi.nlm.nih.gov/pubmed/21833586 http://dx.doi.org/10.1007/s00018-011-0773-8

Ejemplares similares

Nucleoside modifications in the regulation of gene expression: focus on tRNA
por: Duechler, Markus, et al.
Publicado: (2016)

C5-substituents of uridines and 2-thiouridines present at the wobble position of tRNA determine the formation of their keto-enol or zwitterionic forms - a factor important for accuracy of reading of guanosine at the 3΄-end of the mRNA codons
por: Sochacka, Elzbieta, et al.
Publicado: (2017)

Different Oxidation Pathways of 2-Selenouracil and 2-Thiouracil, Natural Components of Transfer RNA
por: Kulik, Katarzyna, et al.
Publicado: (2020)

Novel entry to the synthesis of (S)- and (R)-5-methoxycarbonylhydroxymethyluridines – a diastereomeric pair of wobble tRNA nucleosides
por: Borowski, Robert, et al.
Publicado: (2019)

Efficient access to 3′-O-phosphoramidite derivatives of tRNA related N(6)-threonylcarbamoyladenosine (t(6)A) and 2-methylthio-N(6)-threonylcarbamoyladenosine (ms(2)t(6)A)
por: Debiec, Katarzyna, et al.
Publicado: (2021)

Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression
por: Czernek, Liliana, et al.
Publicado: (2017)

2-Selenouridine, a Modified Nucleoside of Bacterial tRNAs, Its Reactivity in the Presence of Oxidizing and Reducing Reagents
por: Kulik, Katarzyna, et al.
Publicado: (2022)

Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number
por: Pang, Yan Ling Joy, et al.
Publicado: (2014)

Multiple Layers of Stress-Induced Regulation in tRNA Biology
por: Huang, Hsiao-Yun, et al.
Publicado: (2016)

2-Thiouracil deprived of thiocarbonyl function preferentially base pairs with guanine rather than adenine in RNA and DNA duplexes
por: Sochacka, Elzbieta, et al.
Publicado: (2015)

Escherichia coli tRNA 2-Selenouridine Synthase (SelU): Elucidation of Substrate Specificity to Understand the Role of S-Geranyl-tRNA in the Conversion of 2-Thio- into 2-Selenouridines in Bacterial tRNA
por: Szczupak, Patrycja, et al.
Publicado: (2022)

Exosomes as Messengers between Mother and Fetus in Pregnancy
por: Czernek, Liliana, et al.
Publicado: (2020)

CRISPR/Cas9: Principle, Applications, and Delivery through Extracellular Vesicles
por: Horodecka, Katarzyna, et al.
Publicado: (2021)

Critical Minireview: The Fate of tRNA(Cys) during Oxidative Stress in Bacillus subtilis
por: Campos Guillen, Juan, et al.
Publicado: (2017)

Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference
por: Sierant, Malgorzata, et al.
Publicado: (2011)

C5-Substituted 2-Selenouridines Ensure Efficient Base Pairing with Guanosine; Consequences for Reading the NNG-3′ Synonymous mRNA Codons
por: Leszczynska, Grazyna, et al.
Publicado: (2020)

Disrupted tRNA Genes and tRNA Fragments: A Perspective on tRNA Gene Evolution
por: Kanai, Akio
Publicado: (2015)

Structural Insights into tRNA Dynamics on the Ribosome
por: Agirrezabala, Xabier, et al.
Publicado: (2015)

The tRNA Elbow in Structure, Recognition and Evolution
por: Zhang, Jinwei, et al.
Publicado: (2016)

Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function
por: Väre, Ville Y. P., et al.
Publicado: (2017)

Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation
por: Michalska, Karolina, et al.
Publicado: (2021)

Extracurricular Functions of tRNA Modifications in Microorganisms
por: Edwards, Ashley M., et al.
Publicado: (2020)

Dynamics of intracellular stress-induced tRNA trafficking
por: Dhakal, Rabin, et al.
Publicado: (2019)

tRNA Modifications: Impact on Structure and Thermal Adaptation
por: Lorenz, Christian, et al.
Publicado: (2017)

Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase
por: Wu, Jiang, et al.
Publicado: (2014)

S-Geranyl-2-thiouridine wobble nucleosides of bacterial tRNAs; chemical and enzymatic synthesis of S-geranylated-RNAs and their physicochemical characterization
por: Sierant, Malgorzata, et al.
Publicado: (2016)

The structural basis of tRNA recognition by arginyl-tRNA-protein transferase
por: Abeywansha, Thilini, et al.
Publicado: (2023)

The Dihydrouridine landscape from tRNA to mRNA: a perspective on synthesis, structural impact and function
por: Finet, Olivier, et al.
Publicado: (2022)

Change of tRNA identity leads to a divergent orthogonal histidyl-tRNA synthetase/tRNA(His) pair
por: Yuan, Jing, et al.
Publicado: (2011)

The diverse structural modes of tRNA binding and recognition
por: Biela, Anna, et al.
Publicado: (2023)

Synthesis of Nucleobase-Modified RNA Oligonucleotides by Post-Synthetic Approach
por: Bartosik, Karolina, et al.
Publicado: (2020)

RTCB Complex Regulates Stress-Induced tRNA Cleavage
por: Akiyama, Yasutoshi, et al.
Publicado: (2022)

Impact of tRNA Modifications and tRNA-Modifying Enzymes on Proteostasis and Human Disease
por: Pereira, Marisa, et al.
Publicado: (2018)

Mechanisms of tRNA-derived fragments and tRNA halves in cancer treatment resistance
por: Zhang, Yue, et al.
Publicado: (2020)

Evolution of Life on Earth: tRNA, Aminoacyl-tRNA Synthetases and the Genetic Code
por: Lei, Lei, et al.
Publicado: (2020)

Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
por: Khan, Krishnendu, et al.
Publicado: (2022)

Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase
por: Grant, Thomas D., et al.
Publicado: (2012)

The Pros of changing tRNA identity
por: Ibba, Michael
Publicado: (2023)

Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
por: Shen, Ning, et al.
Publicado: (2006)

Stress Response in Entamoeba histolytica Is Associated with Robust Processing of tRNA to tRNA Halves
por: Sharma, Manu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q8vs40gc1ccta8267qhj9ri5ff