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Is cortisol the key to the pathogenesis of delirium after coronary artery bypass graft surgery?

Postoperative delirium is a serious complication of cardiac surgery. However, the pathophysiology of this mental syndrome is largely unknown. Recent findings suggest an association between elevated level of cortisol and postoperative delirium. Further studies should investigate the mechanisms respon...

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Detalles Bibliográficos
Autores principales: Kazmierski, Jakub, Kloszewska, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222018/
https://www.ncbi.nlm.nih.gov/pubmed/21241525
http://dx.doi.org/10.1186/cc9372
Descripción
Sumario:Postoperative delirium is a serious complication of cardiac surgery. However, the pathophysiology of this mental syndrome is largely unknown. Recent findings suggest an association between elevated level of cortisol and postoperative delirium. Further studies should investigate the mechanisms responsible for excessive perioperative cortisol secretion.