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A Lipopeptide Facilitate Induction of Mycobacterium leprae Killing in Host Cells
Little is known of the direct microbicidal activity of T cells in leprosy, so a lipopeptide consisting of the N-terminal 13 amino acids lipopeptide (LipoK) of a 33-kD lipoprotein of Mycobacterium leprae, was synthesized. LipoK activated M. leprae infected human dendritic cells (DCs) to induce the pr...
Autores principales: | Maeda, Yumi, Tamura, Toshiki, Fukutomi, Yasuo, Mukai, Tetsu, Kai, Masanori, Makino, Masahiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222628/ https://www.ncbi.nlm.nih.gov/pubmed/22132248 http://dx.doi.org/10.1371/journal.pntd.0001401 |
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