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Cyclic AMP-Dependent Protein Kinase A Regulates the Alternative Splicing of CaMKIIδ

Ca(2+)/calmodulin-dependent protein kinase (CaMK) IIδ is predominantly expressed in the heart. There are three isoforms of CaMKIIδ resulting from the alternative splicing of exons 14, 15, and 16 of its pre-mRNA, which is regulated by the splicing factor SF2/ASF. Inclusion of exons 15 and 16 or of ex...

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Detalles Bibliográficos
Autores principales: Gu, Qingqing, Jin, Nana, Sheng, Hongzhuan, Yin, Xiaomin, Zhu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222655/
https://www.ncbi.nlm.nih.gov/pubmed/22132070
http://dx.doi.org/10.1371/journal.pone.0025745