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Normalization of High Dimensional Genomics Data Where the Distribution of the Altered Variables Is Skewed
Genome-wide analysis of gene expression or protein binding patterns using different array or sequencing based technologies is now routinely performed to compare different populations, such as treatment and reference groups. It is often necessary to normalize the data obtained to remove technical var...
Autores principales: | Landfors, Mattias, Philip, Philge, Rydén, Patrik, Stenberg, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222656/ https://www.ncbi.nlm.nih.gov/pubmed/22132175 http://dx.doi.org/10.1371/journal.pone.0027942 |
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