Reduced Coupling of Oxidative Phosphorylation In Vivo Precedes Electron Transport Chain Defects Due to Mild Oxidative Stress in Mice

Oxidative stress and mitochondrial function are at the core of many degenerative conditions. However, the interaction between oxidative stress and in vivo mitochondrial function is unclear. We used both pharmacological (2 week paraquat (PQ) treatment of wild type mice) and transgenic (mice lacking C...

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Detalles Bibliográficos
Autores principales: Siegel, Michael P., Kruse, Shane E., Knowels, Gary, Salmon, Adam, Beyer, Richard, Xie, Hui, Van Remmen, Holly, Smith, Steven R., Marcinek, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222658/
https://www.ncbi.nlm.nih.gov/pubmed/22132085
http://dx.doi.org/10.1371/journal.pone.0026963

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